Endothelins (ETs) and sarafotoxins (SRTXs) belong to a family of vasoconstrictor peptides, which regulate pigment migration and/or production in vertebrate pigment cells.The teleost Carassius auratus erythrophoroma cell line, GEM-81, and Mus musculus B16 melanocytes express rhodopsin, as well as the ET receptors, ETB and ETA, respectively.Both cell
Abstract Background Personal digital assistants (PDA) offer putative advantages over paper for collecting research data.However, there are no data prospectively comparing PDA and paper in the emergency department.The aim of this study was to prospectively compare the performance of PDA and paper enrollment instruments with respect to time required
Pancreatic cancer is a devastating disease with a high mortality rate and a Hooks lack of effective therapies.The challenges associated with early detection and the highly aggressive nature of pancreatic cancer have limited treatment options, underscoring the urgent need for better disease-modifying therapies.Peptide-based biotherapeutics have beco